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囊切除病理报告实践的变化 - - 来自对212名病理学家的国际调查结果

Jon Griffin^1,2, Arndt Hartmann^3,4,5, Eva Comperat⁶

¹School of Medicine and Population Health, University of Sheffield, Sheffield, UK. jonathan.griffin@sheffield.ac.uk.

Virchows Archiv : an international journal of pathology

|September 7, 2024

概括

在全球范围内,病理学家对囊切除样本的病理学评估差异很大. 固定,剖析和残留瘤评估的标准化技术对于准确的癌症预后和治疗决策至关重要.

科学领域:

尿路病理学尿路病理学
手术病理学手术病理学
在瘤学瘤学.

背景情况:

对囊切除样本进行准确的病理评估对于癌症分期,预后和指导辅助治疗至关重要.
目前关于囊切除术的最佳固定,剖析,块选择和显微镜评估的证据有限.
在目前的病理实践中,对于囊切除标本存在显著的变化.

研究的目的:

调查目前在囊切除试样病理性评估方面的国际实践.
识别技术的变化,包括固定,剖析和残留瘤评估.
探索数字和分子病理学在囊切除样本分析中的使用.

主要方法:

在212名病理学家中进行了一项国际调查.
该调查评估了样本处理的方法,包括固定和剖析.
研究了评估残留瘤的方法,特别是新辅助化疗后的方法.

主要成果:

在囊切除样本处理的所有阶段,从固定到显微镜评估,都观察到显著的变化.
评估残留瘤的实践,特别是在新辅助化疗后的化疗环境中,显示出相当大的变化,包括不一致的响应评分系统的使用.
在使用数字和分子病理学技术方面注意到了不同的方法.

结论:

对于囊切除样本,缺乏标准化的病理评估协议.
技术的变化会影响预后信息和治疗决策的准确性.
需要进一步的研究,以建立最佳实践,并提高囊切除病理学的一致性.

关键词:

膀癌是一种癌症.囊切除术 (Cystectomy) 是一种切除囊的方法.剖析剖析分解批发批发批发批发批发批发新辅助化学疗法新辅助化学疗法病理反应得分病理反应得分

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