循环炎症标志物和子宫内膜癌的风险:系统性审查和元分析
Haoxin Tina Zheng1, Makayla W C Lou1, Pierre-Antoine Dugué1
1Cancer Epidemiology Division, Cancer Council Victoria, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
炎症可能会增加子宫内膜癌症的风险. 高水平的C-反应蛋白 (CRP) 和瘤亡因子-α (TNF-α) 与风险增加有关,而阿迪波内克丁显示出保护作用.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 流行病学 流行病学
背景情况:
- 炎症被认为是子宫内膜癌发展的一个可疑因素.
- 之前的审查已经分析了有限范围的炎症生物标志物.
- 这项研究全面评估了13种循环炎症生物标志物.
结论:
- 循环炎症生物标志物在子宫内膜癌致癌过程中起作用.
- 这些发现突出了与子宫内膜癌风险相关的特定生物标志物 (CRP,TNF-α,阿迪波涅丁).
- 未来的研究应该采用前性或MR设计,并评估更广泛的炎症标记物.
更多相关视频
07:46Author Spotlight: Advancing Reproductive Immunology with a Protocol for the Quantitative Evaluation of Endometrial Immune Cells
Published on: October 13, 2023
05:16Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
相关概念视频
Disorders of the Female Reproductive System
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
