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IDO1的mRNA递送抑制了T细胞介导的自身免疫

Laurie L Kenney1, Rebecca Suet-Yan Chiu1, Michelle N Dutra1

  • 1Immune Therapeutic Discovery, Moderna, Inc., 325 Binney Street, Cambridge, MA 02139, USA.

Cell reports. Medicine
|September 7, 2024
PubMed
概括

使者RNA (mRNA) 提供了一种新型的膜固的印度氨胺-2,3-二氧化酶 (IDO1),用于治疗自身免疫性疾病. 这种方法通过抑制免疫反应,在多种模型中成功地改善了疾病.

关键词:
美国中央情报局,中央情报局.欧洲电子商务管理局 (EEAE)标签: 标签: IDO1 标签: IDO1 标签: IDO1在T细胞,T细胞.一个GVHDHD.这是自身免疫力.基诺氨酸通路的使用脂质纳米颗粒是一种纳米粒子.它们是mRNARNA.托芬三聚氨酸是什么

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