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Updated: Jun 14, 2025

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帕内特细胞的TNF信号诱导肠道细菌转移和败血症

Charlotte Wallaeys1, Natalia Garcia-Gonzalez1, Steven Timmermans1

  • 1VIB Center for Inflammation Research, VIB, Ghent 9052, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent 9052, Belgium.

Cell host & microbe
|September 7, 2024
PubMed
概括

瘤亡因子 (TNF) 损害了肠道Paneth细胞的抗菌功能,导致细菌转移和败血症. 阻止帕内斯细胞中的TNF受体P55可以防止这种败血症,揭示了宿主防御和疾病的关键机制.

关键词:
帕内特细胞是帕内特细胞.这就是TNF TNF.细菌转位的转位方式干扰子干扰子干扰子不折叠的蛋白质反应反应

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