狗糖尿病中的异位胰腺炎 - 一个活跃的犯罪者?
Arielle Johnson-Pitt1, Brian Catchpole2, Lucy J Davison3
1Department of Clinical Science and Services, The Royal Veterinary College, Hertfordshire AL9 7TA, UK.
Veterinary journal (London, England : 1997)
|September 7, 2024
概括
外分胰腺炎症可能导致β细胞死亡,从而导致犬类糖尿病. 本综述探讨了狗胰腺炎和糖尿病之间的联系和潜在的诊断/治疗方法.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 内分泌学 在内分泌学.
- 胃肠病学 胃肠病学
背景情况:
- 狗糖尿病是一种常见的内分泌疾病.
- 同时的胰腺炎在30%的糖尿病犬中被观察到死后.
- 目前胰腺炎的诊断不准确,两种疾病的治疗都有局限性.
研究的目的:
- 审查关于胰腺外分-内分泌相互作用的科学文献.
- 为了研究胰腺外分炎症在狗糖尿病发病过程中的作用.
- 探索当前和未来的诊断和治疗策略.
主要方法:
- 科学文章的文献评论. 科学文章的文献评论.
- 分析证据,将异位胰腺炎与β细胞损失联系起来.
- 对犬类胰腺炎和糖尿病的诊断和治疗选择的审查.
主要成果:
- 外分胰腺炎是一种潜在的,未被认可的,导致狗的β细胞死亡的原因.
- 导致糖尿病的胰岛素缺乏可能会被胰腺炎加剧.
- 狗糖尿病和胰腺炎的现有治疗方法通常是缓解的,而不是治愈的.
结论:
- 需要进一步的研究来确认外分胰腺炎在狗糖尿病中的直接作用.
- 改善胰腺炎的诊断工具对于早期干预至关重要.
- 针对胰腺炎的根本原因的向治疗可以改善糖尿病狗的治疗结果.
相关概念视频
Chronic Pancreatitis I: Introduction
84
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
84
Acute Pancreatitis II: Clinical Manifestations and Management
111
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
111
Acute Pancreatitis I: Introduction
349
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
349
Pathophysiology of Diabetes
908
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
908
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
1.2K
The pancreatic islets comprising only 1%-2% of the volume are highly vascularized and innervated mini-organs. They contain five endocrine cell types, including β cells that secrete insulin, which is synthesized as a single polypeptide chain, preproinsulin, processed to proinsulin, and finally to insulin and C-peptide. This process is complex and regulated, involving the Golgi complex, the endoplasmic reticulum, and the secretory granules of the β cell.
Insulin and C-peptide are...
Insulin and C-peptide are...
1.2K
Cells and Secretions of the Pancreas
2.1K
The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
2.1K


