一个系统的审查,探索一个神经心理档案,预先厌食症神经性
1Division of Medicine, Eating Disorders and Clinical Nutrition, UCL, London, UK.
概括
精神性厌食症 (AN) 患者的一级亲属表现出认知灵活性和中心连贯性降低,这表明这些特征可能是遗传的内分类型. 这表明AN的潜在神经心理风险概况.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 遗传学 是一个遗传学.
背景情况:
- 精神性厌食症 (AN) 患者表现出认知灵活性和中心连贯性受损.
- 这些认知缺陷甚至在从AN恢复后仍然存在.
- 在一级亲属中可能存在一种潜在的神经心理风险特征.
研究的目的:
- 系统地审查有关AN个人的一级亲属认知灵活性和中心连贯性的研究.
- 确定这些认知障碍是否代表AN的遗传性风险因素.
主要方法:
- 按照PRISMA指南对电子数据库进行系统审查.
- 纳入标准侧重于对AN亲属的神经心理评估.
- 使用批判性评估技能计划评估的偏见风险.
主要成果:
- 审查中包括了10项研究.
- 大多数研究发现,与对照人群相比,AN亲属的认知灵活性和中心连贯性显著下降.
- 对于这些认知障碍,观察到中等到大效应大小.
结论:
- 减少认知灵活性和弱的中心连贯性似乎是AN的内类型.
- 这些发现表明,有潜力开发早期查工具,用于面临AN风险的个体.
- 需要进一步的研究来确认这些生物标志物在家庭与AN.
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