相关实验视频
Updated: Jun 14, 2025
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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
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在高级非黑色素瘤皮肤癌的管理更新
Flora Yan1, Cecelia E Schmalbach1
1Department of Otolaryngology-Head & Neck Surgery, Lewis Katz School of Medicine at Temple Hospital, Philadelphia, PA, USA.
Surgical oncology clinics of North America
|September 7, 2024
概括
针对非黑色素瘤皮肤癌,如基底细胞癌 (BCC) 和皮肤状细胞癌 (cSCC),有新的治疗方法可用. 这些包括先进的疗法,如对具有挑战性的病例的刺抑制剂和免疫检查点抑制剂.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
背景情况:
- 基础细胞癌 (BCC),皮肤状细胞癌 (cSCC) 和默克尔细胞癌 (MCC) 是常见的非黑色素瘤皮肤癌.
- 对这些恶性瘤的治疗策略有显著的进步.
研究的目的:
- 总结目前BCC,cSCC和MCC的治疗进展情况.
- 突出新型治疗方式的指示.
主要方法:
- 对非黑色素瘤皮肤癌的近期治疗进展的综述.
- 确定符合先进治疗条件的患者群体.
主要成果:
- 建议对局部晚期,节点阴性cSCC和MCC进行哨兵淋巴结活检.
- 刺抑制剂对BCC患者有效,这些患者对传统治疗不耐药.
- 免疫检查点抑制剂 (例如,塞米普利马布,潘布罗利祖马布,阿维卢马布,雷蒂芬利马布-dlwr) 为高级或耐火性BCC,cSCC和MCC提供了选择.
结论:
- 非黑色素瘤皮肤癌的现代治疗算法包括先进的全身疗法.
- 向疗法和免疫疗法在管理先进的BCC,cSCC和MCC方面取得了重大进展.
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