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肥胖对肥胖儿童和青少年肺功能的长度影响
Pawinee Charoensittisup1, Kanokporn Udomittipong2, Khunphon Mahoran1
1Division of Pulmonology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
肥胖儿童的腹部脂肪增加会在一年内对肺功能产生负面影响. 腰围 (WC) 和腰高比 (WC/Ht) 的变化与肺功能减弱有关,突出了针对性减肥计划的需要.
科学领域:
- 儿科肺病学 儿科肺病学
- 肥胖问题研究研究
- 公共卫生 公共卫生
背景情况:
- 儿童肥胖是一个越来越令人担忧的潜在的长期健康后果.
- 肥胖对儿科患者肺功能的影响需要进一步的纵向研究.
研究的目的:
- 为了检查肥胖对肺功能变化的纵向影响,在肥胖儿童和青少年的一年.
- 为了确定与肺功能变化相关的肥胖的特定人类指标.
主要方法:
- 招募肥胖儿童和青少年 (8-15岁) 进行基线和1年的随访肺功能测试 (PFT).
- 利用多重线性回归来评估身体质量指数 (ΔBMI),胸围 (ΔCC),腰围 (ΔWC) 和腰高比 (ΔWC/Ht) 变化对肺功能参数的影响.
- 分析了1秒内强制呼气体积/强制生命能力 (ΔFEV1/FVC) 的变化,强制呼气流速在生命能力的25-75% (ΔFEF25-75%) 之间.
主要成果:
- 增加的腰围 (ΔWC) 与 Δ(FEV1/FVC), ΔFEF25-75% 和 Δ(FEF25-75%/FVC) 的下降显著相关.
- 同样,增加的腰与身高的比率 (ΔWC/Ht) 与 Δ(FEV1/FVC), ΔFEF25-75% 和 Δ(FEF25-75%/FVC) 的变化有显著的负相关性.
结论:
- 腹部脂肪的变化,通过WC和WC/Ht测量,在1年内显著损害肥胖儿童和青少年的肺功能.
- 腰围和腰与身高的比例是监测肥胖及其对呼吸系统健康的影响的有价值指标.
- 针对腹部脂肪减少的干预措施对于预防儿童肥胖症的长期肺功能缺陷至关重要.
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