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针对COVID-19病毒的抗病毒疗法:叙事审查和文献计量分析

Saeid Mezail Mawazi¹, Nousheen Fathima², Syed Mahmood³

¹School of Pharmacy, Management & Science University (MSU), Section 13, 40100 Shah Alam, Selangor, Malaysia.

The American journal of emergency medicine

|September 8, 2024

概括

这项研究分析了2019-2022年COVID-19药理治疗方法. 雷梅西维尔和帕克斯洛维德显示有效性,而其他药物有混合的结果,突出结合疗法和正在进行的研究的需要.

科学领域:

药理学药理学是指药理学的学科.
传染性疾病传染性疾病
图书统计学图书统计学

背景情况:

随着COVID-19大流行,导致全球卫生紧急情况,导致数百万人死亡.
对于COVID-19的药理干预措施存在有限的综合性审查.
了解治疗的有效性和安全性对于患者的治疗结果至关重要.

研究的目的:

为了对2019-2022年COVID-19药理治疗方法进行文献计量分析.
检查各种研究药物的安全性和有效性.
确定COVID-19药物研究中的趋势和差距.

主要方法:

对PubMed和ScienceDirect (2019-2022) 的出版物进行了图书统计分析.
专注于COVID-19的药理干预措施.
对特定药物的安全性和有效性数据的审查.

主要成果:

雷梅西维尔 (Veklury®) 和尼尔马特里尔维尔/里托纳维尔 (Paxlovid®) 在减少住院和严重结局方面表现出显著的有效性.
洛皮纳维尔/里托纳维尔 (Kaletra®) 和伊弗梅克丁显示出不一致的结果.
重新利用现有药物是一个关键的快速反应策略.

结论:

结合有效疗法的多方面的治疗方法对于改善患者的治疗结果至关重要.
组合疗法和持续的研究对于优化COVID-19治疗策略至关重要.
需要对药物的作用机制和不良影响进行进一步的研究.

关键词:

在 COVID-19 疫情中,新冠病毒新冠病毒新冠病毒.药理学药理学是指药理学的学科.这就是SARS-CoV-2病毒.治疗方法治疗方法

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