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胃食道逆流性疾病中自主神经系统的功能障碍:对心血管系统的后果
Leila Triki1, Nouha Gammoudi2, Lassaad Chtourou3
1Functional Explorations Department, Habib Bourguiba Hospital, Sfax Tunisia; LR19ES15, Medical School, University of Sfax, Tunisia.
胃食道逆流性疾病 (GERD) 与自主神经系统 (ANS) 失调有关,影响心血管功能. 患有GERD的患者表现出心率变化增加和血压下降受损,这表明自主神经病变.
科学领域:
- 胃肠病学 胃肠病学
- 神经学 神经学
- 心脏病学 心脏病学
背景情况:
- 胃食道逆流性疾病 (GERD) 的病理生理学涉及下胃食道缩体的自主失调.
- 自主神经系统 (ANS) 功能障碍可能超出GERD,影响其他生理系统.
研究的目的:
- 为了研究孤立的GERD患者的自主神经系统 (ANS) 功能.
- 为了确定与GERD相关的自主失调是否会影响心血管调节.
主要方法:
- 一项研究包括11名GERD患者和14名对照组.
- 参与者进行了自主功能测试:COMPASS 31,EMLA,SSR,24小时HRV和ABPM.
主要成果:
- 患有GERD的患者表现出更高的COMPASS 31分数和更高的HRV参数.
- 在GERD患者中观察到夜间血压下降的损伤和阳性EMLA测试.
- 同情皮肤反应 (SSR) 在两组之间没有显著差异.
结论:
- 患有GERD的患者表现出高的副交感音调和心血管自主失衡.
- 自主神经病变可能是GERD的早期表现.
- 对外围小纤维功能的进一步研究是有必要的.
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