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便携式多式平台,使用碳纳米离子作为色度和光信号输出,用于探测素

Yi-Xuan Li¹, Shupei Zhang¹, Yitian Huang¹

¹College of Chemical and Material Engineering, Quzhou University, Quzhou, Zhejiang, 324000, China.

|September 8, 2024

概括

本研究介绍了一种基于纸张的双模式生物传感器,用于疾病生物标志物检测. 这种新型传感器使用双信号通路来提高可靠性,可以通过智能手机或肉眼读取.

科学领域:

生物医学工程生物医学工程
分析化学分析化学
材料科学材料科学材料科学

背景情况:

多模式生物传感器通过独立信号来提高疾病生物标志物检测可靠性.
基于纸质的生物传感器在诊断中提供了便携性和易用性.

研究的目的:

开发一个便携式的,双模式 (色度测量-光) 基于纸张的生物传感器,用于敏感的素检测.
使用PAN/Fe(III) 碳纳米离子 (FPC) 作为信号放大和双模式输出的核心组件.
为了实现可访问的疾病诊断,以视觉和智能手机为基础的检测.

主要方法:

使用聚合物点 (Pdots) 作为光源和PAN/Fe(III) 碳纳米洋 (FPC) 作为光灭剂和纳米酶的双模式生物传感器的制造.
在碳纳米离子 (CNOs) 上缩Fe(III),由1-(2-pyridylazo)-2-naphthol (PAN) 中介,以产生具有模仿酶和光热特性的FPC.
利用FPC的光热转换用于放大色度信号及其吸收特性用于Pdots的光火.

主要成果:

开发的生物传感器展示了用于探测素的双模式 (色度和光) 信号输出.
FPCs表现出极好的模仿酶活性和光热转换能力,导致放大色度信号.
PAN与Fe (III) 的复合促进了Pdots的高效光火,使其能够进行敏感的检测.

结论:

一个方便且便携的色度-光双模式生物传感器已成功开发用于探测素.
生物传感器集成了自我校准和提高疾病生物标志物检测可靠性的功能.
这种方法为开发用于各种疾病诊断的视觉多模式生物传感器提供了一个有希望的平台.

关键词:

碳纳米离子是一种碳纳米离子.能源转移能源转移能源转移多模式生物传感器纳米酶是一种纳米酶.这是一种素, Trypsin.

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