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Updated: Jun 13, 2025

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通过NEDD4L/NF-κB通路,SGK1有助于冠心病中的铁亡

Yong Peng1, Yu Jiang1, Qingfeng Zhou1

  • 1Department of Cardiovascular Surgery, Key Laboratory for Cardiovascular Disease of Yunnan Province, Clinical Medicine Center for Cardiovascular Disease of Yunnan Province, Yan'an Hospital Affiliated to Kunming Medical University, Kunming 650051, China.

Journal of molecular and cellular cardiology
|September 8, 2024
PubMed
概括

这项研究表明,SGK1通过调节NEDD4L-NF-κB通路来促进冠心病 (CHD) 的铁亡. 向SGK1可能为治疗慢性心脏病中的铁亡提供了一个新的治疗策略.

关键词:
冠心病是一种冠心病.内皮细胞是内皮细胞.铁化是铁化的一种.类似于NEDD4的E3无素蛋白联酶.血清/葡萄皮质激素调节激酶1

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