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Updated: Jun 13, 2025

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
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冠状病毒主要蛋白质的结构基础与Bofutrelvir相结合

Wei-Wei Wang1, Pei Zeng2, Tongchao Liu3

  • 1Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201204, China.

Journal of molecular biology
|September 8, 2024
PubMed
概括

博富特雷尔维尔有效抑制SARS-CoV-2和其他冠状病毒的主要蛋白酶 (Mpro). 这种药物为COVID-19治疗和未来的病毒威胁提供了更安全的单疗法选择.

关键词:
新冠病毒新冠病毒新冠病毒.抑制剂的抑制剂主要蛋白质酶的主要蛋白质酶.变种突变者 变种突变者这就是SARS-CoV-2病毒.

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