探讨临床检查结果,主观报告的症状和客观鼻阻塞的鼻受试度指标之间的关系:一项基线NAIROS子研究分析
Pavithran Maniam1, Alison Bray2,3, Michael Drinnan2,3
1Ear, Nose & Throat Department, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
概括
像鼻分区比率 (NPR) 这样的客观鼻腔通透度指标与患者报告的症状和临床医生对鼻腔阻塞的评估有很强的相关性. 这些发现支持使用客观措施与临床检查一起用于更好的诊断和治疗规划.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 鼻科 鼻科是指鼻科的专家.
- 医学诊断 医学诊断 医学诊断
背景情况:
- 客观的鼻空气流量测量的诊断价值,如鼻吸气流量峰值 (PNIF) 和鼻吸管测量,结合对血管整形候选人的临床评估,尚未得到充分确立.
- 了解这些关系对于完善手术指示和患者选择至关重要.
研究的目的:
- 调查临床检查结果,主观症状报告和客观鼻腔通透度测量在经历鼻腔阻塞的个体之间的基线相关性.
- 评估客观措施的有用性,以补充主观和临床评估.
主要方法:
- NAIROS试验的一项子研究包括由于隔膜偏差导致鼻腔阻塞的参与者.
- 临床评估包括隔膜偏差侧面,较低的轮 (IT) 状态,需要减少IT,气道阻塞 (观察员评级的气道阻塞 - ORAB) 和主观鼻腔阻塞 (双正则评估主观量表 - DOASS).
- 客观措施包括PNIF和鼻分泌计,以评估鼻分离比率 (NPR).
主要成果:
- 在主观的DOASS得分和客观的NPR测量之间观察到强烈的相关性 (r=+0.737,p<0.001).
- 鼻分离比率 (NPR) 根据隔膜偏差的侧面 (p<0.001) 显示出显著差异,并与临床医生的气道阻塞程度相关 (ORAB>50%与<50%,p=0.002).
- 在需要减少IT和PNIF变化之间发现了微弱的相关性 (r=0.13,p<0.01).
结论:
- 在隔膜偏斜的侧面,患者报告的DOASS和客观NPR测量之间存在强烈的关系.
- 客观的NPR测量和临床医生的气道阻塞评估显示出一致性.
- 这些发现表明,客观的鼻腔通透度测量可以有效地支持鼻腔阻塞患者的临床评估.
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