五重复的坐立测试作为高风险COPD患者的死亡率预测器
Roberto Bernabeu-Mora1, Elisa Valera-Novella2, Elodia Teresa Bernabeu-Serrano3
1Department of Pneumology, Hospital General Universitario Morales Meseguer, Murcia, Spain; Department of Internal Medicine, University of Murcia, Murcia, Spain; Research Group Fisioterapia y Discapacidad, Instituto Murciano de Investigación Biosanitaria (IMIB), Murcia, Spain.
在慢性阻塞性肺病 (COPD) 风险标准中添加五次重复的坐立测试 (5-STS),可显著增加死亡率预测. 高风险慢性肺炎患者的5STS表现不佳表明五年死亡率大幅上升.
科学领域:
- 肺部医学 肺部医学
- 老年病的医生 老年病的医生
- 临床流行病学临床流行病学
背景情况:
- 慢性阻塞性肺病 (COPD) 具有显著的死亡风险.
- 目前的风险分层工具,如GesEPOC指南,旨在识别高风险患者.
- 五次重复的坐立测试 (5-STS) 是一种功能性表现测量方法.
研究的目的:
- 评估是否将5-STS测试纳入现有的COPD高风险标准可以改善死亡预后.
- 评估5STS表现对COPD门诊患者5年死亡率的影响.
主要方法:
- 一项观察性研究跟踪了137名COPD门诊患者5年.
- 患者根据GesEPOC 2021标准和5-STS表现 (贫困与非贫困) 进行了分层.
- 统计分析包括卡普兰-梅尔,考克斯的比例风险和回归模型.
主要成果:
- 总体而言,5年死亡率为27%.
- 高风险患者的死亡率比低风险患者 (13.6%) 高 (29.6%).
- 在高风险患者中,5-STS表现不佳与5年死亡率显著增加 (60.5%对11.1%) 有关,并且独立地与风险增加相关 (HR 4.70).
结论:
- 在5-STS测试中表现不佳是高风险COPD患者死亡率的重要独立预测因素.
- 将5-STS测试添加到当前的风险标准中,可以提高COPD死亡率的预后准确性.
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