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Updated: Jun 13, 2025

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method
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Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method

Published on: May 2, 2025

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人类领先链的结构 Polε-PCNA全酶

Qing He1, Feng Wang1, Nina Y Yao2

  • 1Department of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA.

Nature communications
|September 8, 2024
PubMed
概括

人类DNA聚合酶epsilon (Polε) 通过一种新的三点接口与PCNA进行相互作用. 这种结构揭示了Polε如何结合PCNA来调节DNA合成.

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