相关实验视频

Updated: Jun 13, 2025

Production of Germ-Free Fast-Growing Broilers from a Commercial Line for Microbiota Studies

Production of Germ-Free Fast-Growing Broilers from a Commercial Line for Microbiota Studies

Published on: June 18, 2020

宿主基因和肠道微生物群协同调节卵型的料利用率

Wenxin Zhang¹, Fangren Lan¹, Qianqian Zhou¹

¹State Key Laboratory of Animal Biotech Breeding and Frontier Science Center for Molecular Design Breeding, China Agricultural University, Beijing, 100193, China.

Journal of animal science and biotechnology

|September 8, 2024

概括

宿主遗传和肠道微生物群对家禽料效率产生重大影响. 向特定的肠道细菌和宿主基因可以改善产母的料转换率和剩余料摄入量.

科学领域:

禽类遗传学和微生物学
动物营养和新陈代谢

背景情况:

料效率是家禽业的关键经济特征.
主体遗传和肠道微生物群都在决定料效率方面发挥着作用.
宿主基因,肠道微生物群和晚期产卵母的料效率之间的相互作用尚未得到充分理解.

研究的目的:

研究宿主遗传,肠道微生物群和产母的料效率之间的关联.
确定影响料效率的关键遗传变异,基因和微生物种类.
了解宿主遗传和肠道微生物群对料效率的综合影响.

主要方法:

在686只母的全基因组再测序和肝脏转录基因组测序.
16S rRNA基因测序来自705个个体的肠和便样本.
基因组,转录组和微生物组数据的综合生物信息分析.

主要成果:

料转换比率 (FCR) 和剩余料摄入量 (RFI) 的遗传概率估计分别为0.28和0.48.
肠道微生物群解释了高达20%的RFI变异和15%的FCR变异.
四个基因 (SUCLA2,TNFSF13B,SERTM1,MARVELD3) 被确定为影响料效率的基因,与宿主遗传变异和微生物丰富的特定关联 (例如,Enterococcus,Corynebacteriaceae).

结论:

宿主基因和肠道微生物群都是料效率变化的重要驱动因素.
特定的肠道微生物与宿主基因之间的相互作用共同提高了料效率.
针对肠道微生物群组成和宿主遗传选择的策略可以提高产卵母的料效率.

关键词:

料效率料效率是指料的使用效率.遗传变异遗传变异遗传变异我们的肠道微生物群.产卵母产卵母产卵母是一个多个omics的多个omics.

更多相关视频

Author Spotlight: Advancing Intestinal Bacteria Cultivation for Poultry

Author Spotlight: Advancing Intestinal Bacteria Cultivation for Poultry

Published on: May 10, 2024

In Ovo Feeding of Commercial Broiler Eggs: An Accurate and Reproducible Method to Affect Muscle Development and Growth

In Ovo Feeding of Commercial Broiler Eggs: An Accurate and Reproducible Method to Affect Muscle Development and Growth

Published on: September 20, 2021

相关概念视频

Background and Environment Affect Phenotype

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...