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Updated: Jun 13, 2025

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
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Published on: November 25, 2017

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解码曼诺斯受体-mAb相互作用:高曼诺斯N-甘氨酸和甘氨酸配对的重要性

Julia Baumeister1,2, Maximilian Meudt1,3, Sybille Ebert4

  • 1Analytical Development Biologicals, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.

mAbs
|September 9, 2024
PubMed
概括

这项研究表明,曼诺糖受体 (MR) 与单克隆抗体 (mAbs) 上的高曼诺糖N-甘结合,这可能解释了更快的清除速度,并告知了治疗性抗体开发策略.

关键词:
在N-glycosylation的过程中.在SPR中使用SPR.亲缘关系染色图学 亲缘关系染色图学糖甘配对的配对方法是含有高曼诺斯的高曼诺斯的曼诺糖受体的受体为曼诺糖受体.这是一种单克隆抗体.药物动力学 药物动力学

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