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Updated: Jun 13, 2025

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
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Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA

Published on: February 1, 2019

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新型内源性工程平台,通过细胞外囊进行功能mRNA的强大加载和传递

Antje M Zickler1,2,3, Xiuming Liang1,2,3,4, Dhanu Gupta1,2,5

  • 1Division of Biomolecular and Cellular Medicine, Department of Laboratory Medicine, Karolinska Institutet, ANA Futura, Alfred-Nobels-Allé 8, Huddinge, Stockholm, 14152, Sweden.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|September 9, 2024
PubMed
概括

这项研究开发了一个新的生物工程平台,使用细胞外囊泡 (EVs) 进行高效的信使RNA (mRNA) 传递. 这种先进的系统增强了mRNA疗法,在临床前癌症模型中显示出高疗效.

关键词:
生物工程是生物工程.癌症免疫疗法免疫疗法药物输送是药物输送的过程.细胞外囊泡中的细胞外囊泡.纳米技术是纳米技术.核酸治疗药物 核酸治疗药物

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