缺铁性贫血和牙破:系统性审查和元分析
Rubén Aguirre-Ipenza1, Wendy Nieto-Gutiérrez2, Winnie Contreras3
1Faculty of Health Sciences, Universidad Continental, Lima, Perú.
Global pediatric health
|September 9, 2024
概括
缺铁性贫血 (IDA) 与儿童和青少年牙变风险更高有显著联系. 需要进一步的研究来证实这种联系,并指导公共卫生干预措施.
科学领域:
- 儿科健康 儿科健康
- 口腔健康 口腔健康
- 营养科学 营养科学
背景情况:
- 缺铁性贫血 (IDA) 是儿童和青少年普遍存在的营养缺乏症.
- 牙损仍然是一个重要的公共卫生问题,在世界各地的儿科人口.
- IDA和牙腐烂之间的潜在联系需要进一步调查,以告知预防策略.
研究的目的:
- 系统地评估现有证据,关于缺铁性贫血和儿童和青少年牙损伤之间的关联.
- 通过元分析综合相关研究的发现,以量化关联的强度.
主要方法:
- 在四个国际数据库中进行了全面的文献搜索,截至2023年10月.
- 包括的研究集中在6个月至18岁的个体上,检查了IDA和牙损伤之间的关系.
- 偏差风险使用纽卡斯尔太华尺度进行评估,使用随机效应模型进行定量合成.
主要成果:
- 总共有1161项研究被确定,其中9项被纳入了元分析.
- 在IDA和牙之间发现了显著的关联 (OR:3.54,95%CI:2.54-4.94).
- 患有IDA的个人表现出更高的牙损伤率 (MD: 1.96,95% CI: 1.07-2.85),尽管证据的确定性被评为非常低.
结论:
- 这项研究表明,缺铁性贫血和儿童和青少年的牙损伤之间存在显著的关联.
- 由于方法的局限性和证据的确定性非常低,应谨慎解释结果.
- 建议将口腔健康策略纳入贫血控制计划,强调需要高质量的研究.
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