胃肠道流体瘤 (GIST) 伪装为胰腺伪囊:一个罕见的病例报告
Sarthak Sharma1, Varun Shetty1, Iqbal M Ali1
1General Surgery, Dr. D.Y. Patil Medical College Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pimpri, IND.
Cureus
|September 9, 2024
概括
本案例研究详细介绍了在胃中发现的一种罕见的恶性上皮质肠道 stromal 瘤 (GIST). 手术切除和伊马替尼布治疗是控制这种侵袭性介质细胞瘤的关键.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 病理学 病理学 病理学
背景情况:
- 胃肠道 stromal 瘤 (GIST) 是最常见的肠道介质瘤,虽然相对罕见.
- 恶性表皮性GIST是一种不常见的亚型,具有潜在的攻击性行为.
研究的目的:
- 报告一种罕见的恶性上皮状GIST病例,呈现为囊性病变.
- 突出GISTs的诊断和管理挑战.
- 讨论侵略性GIST的手术和辅助治疗方法.
主要方法:
- 一个62岁的女性的病例介绍,她有腹部疼痛和可触摸的质量.
- 诊断工作包括放射性成像和组织病理学检查 (HPE).
- 手术切除 (子总胃切除,GJ,JJ,切除) 以手术内冷切除为指导,随后进行免疫组织化学分析 (IHC) 和辅助性意马替尼布化疗.
主要成果:
- 组织病理学证实一种来自胃的恶性表皮性GIST具有攻击性特征 (高线粒活性,肝脏透).
- 免疫组织化学显示CD117的阳性和CD34,Desmin和DOG-1的阴性.
- 患者经历了成功的手术切除和辅助意马提尼布治疗.
结论:
- 恶性表皮性GIST可以异常呈现,需要迅速的手术干预.
- 包括手术,病理学和辅助治疗在内的多学科管理对于积极的GIST至关重要.
- CD117阳性是GIST的标志,有助于诊断.
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