新的N-phenylpyrrolamide DNA 陀螺酶抑制剂,具有改善的抗菌活性

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Updated: Jun 13, 2025

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
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Andrej Emanuel Cotman1, Federica Fulgheri1, Martina Piga1

  • 1University of Ljubljana, Faculty of Pharmacy Aškerčeva cesta 7 1000 Ljubljana Slovenia nace.zidar@ffa.uni-lj.si.

RSC advances
|September 9, 2024
PubMed
概括

研究人员发现了新的N-phenylpyrrolamide化合物,可以抑制细菌DNA旋转酶,对阳性和阴性细菌表现出强大的抗菌活性. 与现有的治疗方法相比,这些选择性抑制剂提供了更好的疗效和减少了耐药性的发展.

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