肺高血压中的三环状平面缩外流 - 超越部门平面的移动
Kenzo Ichimura1,2,3, Bettia E Celestin1,3,4, Shadi P Bagherzadeh4
1Department of Medicine, Division of Pulmonary Allergy and Critical Care Stanford University Stanford CA USA.
Pulmonary circulation
|September 9, 2024
概括
在肺动脉高血压 (PAH) 患者中测量三环状平面缩外流 (TAPSE) 的不同方法是不可互换的. 三柱角-角位移 (Tricuspid apico-annular displacement,TADD) 显示了与不良结果的最强相关性.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 肺高血压是什么意思 肺高血压
背景情况:
- 三环状平面缩外流 (TAPSE) 是右心室 (RV) 缩功能的一个关键的心声测量.
- 使用部门线的标准M模式TAPSE测量可能不会准确地反映真实的解剖RV缩短.
- 肺动脉高血压 (PAH) 显著影响RV功能,使得准确的TAPSE评估对预后至关重要.
研究的目的:
- 为了比较不同的测量TAPSE的方法,包括M模式和2D回声心脏学与各种参考线.
- 评估解剖学和基于部门的TAPSE测量之间的一致性.
- 评估不同TAPSE测量技术在PAH患者的预后价值.
主要方法:
- 148名PAH患者接受了跨胸腔心声扫描 (TTE) 和右心导管治疗.
- 使用M模式 (部门,解剖学),2D (部门,解剖学) 和三角形角-角位移 (TAAD) 来测量TAPSE.
- 通过变化系数 (COV),斯皮尔曼相关性和布兰德-阿尔特曼分析来评估协议;使用ROC和卡普兰-梅尔分析确定预后值.
主要成果:
- 在解剖和部门M模式TAPSE (COV 15.5%) 之间观察到良好的一致性.
- 在解剖学M模式TAPSE和TAAD (COV 30.5%) 之间发现了显著的差异.
- 解剖学2DTAPSE与解剖学M模式TAPSE (COV 11.8%) 有很好的一致性.
- 三柱角-角位移 (Tricuspid apico-annular displacement,TADD) 显示,与5年死亡率或肺移植的相关性最强 (C统计值为0.64).
结论:
- 在临床实践中,测量TAPSE的不同方法是不可互换的.
- 测量技术的选择可以影响RV功能和患者预后的评估.
- 三柱角-角位移 (Tricuspid apico-annular displacement,TADD) 可能为PAH患者提供更好的预后信息.
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