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Updated: Jun 13, 2025

Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
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RUNX1-PDIA5轴通过调节CCAR1蛋白表达来促进质母细胞瘤的恶性进展

Qiankun Ji1,2,3,4,5, Zewei Tu1,2,3,4, Junzhe Liu1,2,3,4

  • 1Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P. R. China.

International journal of biological sciences
|September 9, 2024
PubMed
概括

蛋白二硫化异构酶A5 (PDIA5) 在多形质母细胞瘤 (GBM) 中过度表达,导致瘤的进展和入侵. 针对PDIA5及其调节轴 (RUNX1/PDIA5/CCAR1) 可能提供新的质母细胞瘤治疗策略.

关键词:
在CCAR1中,它是CCAR1.在PDIA5中,PDIA5是指PDIA5.在RUNX1中,使用RUNX1.质母细胞瘤多形恶性功能 恶性功能

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