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Updated: Jun 13, 2025

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IL-6信号加速铁过载,通过对内皮细胞中的DMT1进行上调来促进大动脉解剖

Qiang Xie1,2, Jianji Wang1, Runqiao Li1

  • 1Department of Cardiovascular Surgery, Beijing Aortic Disease Center, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

International journal of biological sciences
|September 9, 2024
PubMed
概括

铁过载通过通过IL-6/JAK/STAT通路增加DMT1表达,有助于大动脉解剖 (AD). 阻止这种途径和铁积累改善了AD模型中的生存率和减少了器官损伤.

关键词:
大动脉切割剖析.双价金属运输机 1 双价金属运输机 1细胞内膜网膜的压力应激铁过载是什么?铁过载是什么?一个单细胞RNA测序.

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