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Updated: Jun 13, 2025

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合成方法对抗体结合金纳米颗粒针对性治疗功能的影响

Adi Anaki1, Chen Tzror-Azankot1, Menachem Motiei1

  • 1Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar-Ilan University Ramat Gan 5290002 Israel rachela.popovtzer@biu.ac.il.

Nanoscale advances
|September 9, 2024
PubMed
概括

抗体与金纳米粒子 (GNP) 的共价结合比物理吸附更能增强癌细胞的杀死. 优化抗体质量和链接器组成进一步增强了针对性治疗的抗癌功能.

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Immunogold Electron Microscopy01:20

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Immunoelectron microscopy utilizes immunogold labeling of endogenous proteins with specific antibodies to detect and localize these proteins in cells and tissues. The procedure provides insights into the distribution and quantification of protein under different stimulation conditions offering clues about their functions. Conjugating highly electron-dense gold particles with primary or secondary antibodies allow antigen detection on and within cells, with high resolution and specificity.
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