阻塞性睡眠呼吸暂停-呼吸暂停综合征中的多囊性卵巢综合征:更新的元分析
Jie He1,2,3, Xia Ruan1,4, Jia Li1,2
1Clinical Medical College of Chengdu Medical College, Chengdu, Sichuan, China.
Frontiers in endocrinology
|September 9, 2024
概括
阻塞性睡眠呼吸暂停-呼吸暂停综合征 (OSAHS) 在患有多囊性卵巢综合征 (PCOS) 的女性中很常见. 这种情况与PCOS患者的代谢健康和肥胖程度的恶化有关,需要早期检测和管理.
科学领域:
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
- 代谢健康 代谢健康
背景情况:
- 多囊性卵巢综合征 (PCOS) 经常与阻塞性睡眠呼吸暂停-缺综合征 (OSAHS) 相关.
- 与一般人群相比,患有PCOS的女性的OSAHS发病率更高.
- 代谢功能障碍是PCOS妇女的一个关键问题.
研究的目的:
- 为了评估被诊断为PCOS的女性OSAHS的发病率.
- 为了研究PCOS的OSAHS阳性和OSAHS阴性女性之间的代谢差异.
- 综合目前关于OSAHS和PCOS共患病症的证据.
主要方法:
- 对21项研究进行了系统的元分析.
- 搜索的数据库包括PubMed,EMBASE,科学网,CNKI和万芳.
- 统计分析涉及使用RevMan 5.2和Stata 11.0.0计算加权平均差异 (WMDs) 和标准化平均差异 (SMDs).
主要成果:
- 在患有PCOS的女性中,OSAHS的患病率为20.8%.
- 在各种子组 (种族,年龄,BMI,疾病严重程度) 中观察到OSAHS的较高发病率.
- 与单独患有PCOS的女性相比,患有PCOS和OSAHS的女性的代谢指标和代谢综合征参数明显差.
结论:
- 在患有PCOS的女性中,OSAHS非常普遍,并且与较差的代谢健康和肥胖有关.
- 临床医生应优先考虑在被诊断为PCOS的妇女中对OSAHS进行查.
- 有效管理OSAHS可能会改善这个患者群体的代谢结果.
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