相关实验视频

Updated: Jun 13, 2025

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry
09:31

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

Published on: March 7, 2019

10.6K

粉样β寡合物的度升高及其对与年龄相关的白内障产生预的作用

Peimin Lin1,2,3,4, Jie Xu1,2,3,4, Fan Yang1,2,3,4

  • 1Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|September 9, 2024
PubMed
概括

粉样β oligomers (AβOs) 在与年龄相关的白内障 (ARC) 透镜中积聚,损害细胞功能. 抑制线粒体摄取减少了AβO诱导的细胞死亡,这表明了ARC的新治疗点.

关键词:
这就是 ARC ARC.更多 更多 更多 更多与年龄相关的白内障粉胺-β 寡合物的恒常性是的恒常性.

更多相关视频

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP07:55

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP

Published on: October 17, 2015

11.8K
Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons06:23

Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons

Published on: October 30, 2018

8.0K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
9.3K