患有腹腔大动脉动脉瘤遗传的人群中的焦虑和疾病意识
Nina Fattahi1,2,3, Olga Nilsson3,4, Sverker Svensjö5,6
1Department of Clinical Science and Education, Karolinska Institutet at Södersjukhuset, Stockholm, Sweden.
Journal of medical screening
|September 9, 2024
概括
在成年后代中,对腹腔大动脉瘤 (AAA) 遗传性的认识很高,许多人经历了焦虑. 目前针对AAA风险的医疗保健沟通策略不足,需要改善对家庭的接触.
科学领域:
- 心血管医学 心血管医学
- 遗传学和可遗传性 遗传学和可遗传性
- 心理健康 心理健康
背景情况:
- 腹腔大动脉瘤 (AAA) 具有已知的遗传成分,一级亲属面临更高的风险.
- 这种遗传意识对成年后代的心理影响仍然在很大程度上未被探索.
- 了解亲属的焦虑和生活质量对于有效的风险沟通至关重要.
研究的目的:
- 调查AAA患者成年后代对AAA遗传性和相关焦虑的认识.
- 为了比较男性和女性后代和对照组之间的意识和焦虑水平.
- 评估与有或没有大动脉病理的参与者的与健康有关的生活质量.
主要方法:
- 一项对752名成年后代和756名匹配对照的横截面研究,来自首级亲属检测腹腔大动脉动脉瘤试验 (DAAAD).
- 在主动脉超声波之前,通过与健康相关的生活质量和遗传意识的问卷收集的数据.
- 在不同群体之间比较出勤率,遗传意识,焦虑程度和生活质量.
主要成果:
- 在有AAA家族史的人群中观察到更高的出席率 (67%与52%对比).
- 显著比例的成年后代 (65%) 意识到他们家族的AAA史,与对照人群相比,女性 (38%) 和男性 (32%) 的意识更高.
- 大多数有意识的参与者报告了焦虑 (54%的女性,51%的男性);没有发现生活质量的显著差异.
结论:
- 成人后代中遗传意识和焦虑的高患病率表明,通过当前的医疗保健道进行的风险沟通不足.
- 需要有针对性的策略来改善向患者及其家人传达AAA风险的沟通.
- 解决遗传风险对心理的影响对于全面的患者护理至关重要.
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