左心室尺寸较小,但在青少年和成年人中保留了功能,早产
Gregory P Barton1, Alvin Chandra1, Nataly Sanchez-Solano2
1Department of Internal Medicine University of Texas Southwestern Medical Center Dallas TX.
Journal of the American Heart Association
|September 9, 2024
概括
过早出生的成年人心脏较小,但心脏功能正常. 这项研究研究了早产期个体的心脏结构和功能,发现尽管心脏体积和质量减少,但整体心脏功能仍然保持不变,而与满期同龄人相比.
科学领域:
- 心脏病学 心脏病学
- 新生儿科学 新生儿科学
- 公共卫生 公共卫生
背景情况:
- 过早出生的人在以后的生活中面临心血管疾病的风险较高.
- 对于美国出生的早产人口,心脏病数据有限.
- 了解早产儿的长期心脏健康至关重要.
研究的目的:
- 评估早产青少年和成人的左心室 (LV) 结构和功能.
- 在这个人群中使用同位数手握运动来评估透缩功能.
- 为了比较早产和满期出生的个体之间的心脏参数.
主要方法:
- 招募的青少年和成年人出生中度到极度早产 (≤32周怀孕或<1500g) 和全程对照.
- 进行人体测量,生命体征测量和心声回声仪在休息状态和在同度握手运动期间.
- 分析了左心室 (LV) 结构,静脉缩和腹缩功能以及血液动力学反应.
主要成果:
- 预产期参与者比术语对照人更短,BMI更高.
- 不到期的个体表现出较小的LV终端-透析体积指数,LV中风体积指数和LV质量指数.
- 在早产个体中,静止时观察到 LV 缩和早期透缩组织速度的亚临床降低.
结论:
- 过早出生的青少年和成年人通常表现出正常的心脏功能.
- 尽管心脏体积和质量较小,但整体心脏功能与满期出生的人相比保持不变.
- 对心脏结构和功能的最显著影响是在最早的妊娠年龄观察到的.
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