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Updated: Jun 13, 2025

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells
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Induction and Assessment of Class Switch Recombination in Purified Murine B Cells

Published on: August 13, 2010

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在人类B细胞中类交换重组的定向规则

Likun Du1, Valentyn Oksenych1,2, Hui Wan1

  • 1Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

Journal of immunology (Baltimore, Md. : 1950)
|September 9, 2024
PubMed
概括

我们开发了一种高通量测序方法,用于分析人类B细胞中的Ig类切换重组 (CSR). 这揭示了两个不同的CSR连接模式,一个与DNA修复途径相关,另一个与替代连接机制相关.

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Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches

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