APOBEC家族重塑了清细胞细胞癌中的免疫微环境和治疗敏感性

Guiying Huang1,2, Xianlin Zhan3, Lihong Shen1,4

  • 1Department of Clinical Laboratory, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

PubMed
概括

这项研究在清细胞细胞癌 (ccRCC) 中确定了两种不同的APOBEC亚型,揭示了亚型特定的临床特征,免疫微环境和治疗反应. 准APOBEC3B为ccRCC提供了一个潜在的新治疗策略.

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