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使用基于Pyrene的MOF固体相提取的果天然产品的回收

Tara Hurley¹, Vincent T Remcho¹, Kyriakos C Stylianou¹

¹Department of Chemistry, Oregon State University, Corvallis, OR, 97331, United States.

Chemistry (Weinheim an der Bergstrasse, Germany)

|September 9, 2024

概括

本研究引入了一种新的金属有机框架固体相提取 (MOF-SPE) 方法,用于回收生物活性果天然产品 (BNPs). 与Zr-NU-1000相比,Al-PyrMOF表现出比Zr-NU-1000更好的BNPs的回收和度.

科学领域:

分析化学分析化学
材料科学材料科学材料科学
自然产品化学自然产品化学

背景情况:

生物活性果天然产品 (BNPs) 具有显著的健康益处.
有效的回收方法对于分离和研究这些有价值的化合物至关重要.
传统的提取技术可能是低效和环境负担.

研究的目的:

开发和评估一种使用金属有机框架 (MOF) 的新型固体相提取 (SPE) 方法,用于回收生物活性果天然产品 (BNPs).
为了比较两种以烯为基础的MOF,Al-PyrMOF和Zr-NU-1000在捕获和消化特定BNPs方面的性能.
为了确定最佳的MOF-SPE吸附剂,以有效地恢复BNP.

主要方法:

散散固相提取 (d-SPE) 采用了两种基于烯的MOF:Al-PyrMOF和Zr-NU-1000.
MOFs被测试了它们在随着时间的推移捕获单个BNPs (酸,酸,酸,p-酸) 和BNP混合物的能力.
在不同度下量化了BNP捕获效率,变化,回收和提取因素.

主要成果:

Zr-NU-1000显示了个别BNPs的更高和更一致的捕获,在36小时内达到90%以上.
在捕获50μg/ml的BNP混合物方面,Al-PyrMOF的表现优于Zr-NU-1000,捕获率超过70%.
阿尔-PyrMOF表现出优异的BNP回收,产量至少是回收量的两倍,并且在15μg/mL时获得了2.71的Quercetin的最大提取系数.

结论:

阿尔-PyrMOF是一种有效的MOF-SPE吸收剂,用于有效回收和缩生物活性果天然产品 (BNPs).
MOF的结构拓显著影响了它们在BNP捕获和回收方面的表现.
这种MOF-SPE方法为从复杂矩阵中分离有价值的BNPs提供了一个有希望的替代方案.

关键词:

金属有机框架的框架.自然产品是天然产品.恢复恢复恢复恢复恢复再生再生再生的过程固相提取固相提取的方法

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