癌症患者死亡前六个月患者患者患者报告结果的差异
Samantha Tam1,2, Nada Al-Antary2, Eric Adjei Boakye1,2
1Department of Otolaryngology-Head and Neck Surgery, Henry Ford Hospital, Detroit, MI.
JCO oncology practice
|September 9, 2024
概括
患者报告的结果测量 (PROM) 显示,临终癌症患者的身体功能恶化,疲劳增加,疼痛干扰增加. 常规收集的PROM可以显示早期支持性护理干预的终端阶段.
科学领域:
- 在瘤学瘤学.
- 健康 结果 研究 研究 结果
- 抚慰性护理是一种缓解性护理.
背景情况:
- 患者报告的结果指标 (PROM) 提供了对患者经验的宝贵见解,补充了临床评估.
- 了解生命末期PROM的实时变化对于及时干预至关重要.
- 关于癌症患者生命最后几个月的PROM得分轨迹的数据有限.
研究的目的:
- 为了评估癌症患者在死亡6个月内和幸存癌症患者之间的平均PROM分数的差异.
- 为了确定特定的PROM域,随着癌症患者的生命结束的临近,这些域在癌症患者中发生显著变化.
主要方法:
- 使用国家卫生研究院患者报告结果测量信息系统 (PROMIS) 仪器进行了回顾性病例控制研究.
- 病例:癌症患者在PROM完成后6个月内死亡. 控制组:匹配幸存的癌症患者 (1:3比).
- 概括估计方程模型评估了疼痛干扰,身体功能,疲劳和抑郁症的平均PROM得分的差异.
主要成果:
- 在调整后,在病例和对照之间观察到PROM平均得分的显著差异.
- 身体功能在病例中出现了最大的下降 (平均得分下降了6.52分).
- 与对照组相比,病例报告的疲劳增加 (4.83个点高) 和疼痛干扰 (4.33个点高) 增加.
结论:
- 在死亡6个月内,癌症患者在身体功能,疲劳,疼痛干扰和抑郁等领域的PROM分数显著下降.
- 常规收集的PROM可以作为癌症患者生命末期阶段的实时指标.
- 这些发现支持使用PROM来早期识别需要增强支持性瘤服务的患者.
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