在急性轻度缺血性中风患者或短暂缺血性发作患者中, perfusion 变量与功能性结果的关联
Zhangyan Hou1, Mingwei Ma1, Dongxue Ding1
1Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 215006, China.
概括
超过16.5毫升的不匹配体积可以预测轻度中风或短暂性缺血性发作 (TIA) 患者的预后不佳. 这种成像指标有助于在90天内识别具有较高风险的个人不良功能结果.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 临床医学 临床医学
背景情况:
- 急性轻度中风和过渡性缺血性心脏病发作 (TIA) 患者可能面临不良预后.
- 有限的研究存在于这些患者的功能预后的成像指标.
- perfusion 变量需要进一步研究它们的预测值.
研究的目的:
- 探索轻度缺血性中风或TIA患者的输液变量和不良预后之间的关系.
- 识别可预测功能结果的成像指标.
- 评估与这组患者的临床结果相关的风险因素.
主要方法:
- 从2016年1月到2022年3月,对344名轻度中风或TIA患者 (NIHSS ≤5) 的回顾性分析.
- 糟糕的结果定义为90天后mRS得分≥2.
- 使用多变量逻辑回归和ROC分析来确定预测因素和切断值.
主要成果:
- 49名 (12.4%) 患者在3个月后的预后不佳.
- 不匹配的体积被确定为90天预后不佳的独立预测因素.
- 不匹配量>16.5毫升与不良结果的风险更高有关.
结论:
- ≥16.5毫升的不匹配体积预测轻度中风或TIA患者的功能性结果不佳.
- 不匹配量是预后评估的有价值的成像生物标志物.
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