成人类型扩散性质瘤的质子疗法:系统性审查
Nicolas Goliot1, Selim Mohssine1, Dinu Stefan2
1François Baclesse Comprehensive Cancer Center, Radiation Oncology Department, Caen 14000, France; Cyclhad, Normandy Proton Therapy Center, Caen 14000, France; Normandie Univ., UNICAEN, CNRS, ISTCT, GIP CYCERON, Caen 14000, France.
Critical reviews in oncology/hematology
|September 9, 2024
概括
质子疗法为成年人扩散性质瘤提供了与传统放射治疗相似的生存率. 这种先进的辐射技术可以提高治疗耐受性,减少副作用,特别是神经认知方面的副作用.
科学领域:
- 神经瘤学神经瘤学
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
背景情况:
- 成人类型的扩散性质瘤,包括IDH突变质瘤 (世卫组织2-3级) 和质母细胞瘤,在神经瘤学中构成重大挑战.
- 评估先进的放射治疗技术,如质子疗法,对于优化治疗结果和最大限度地减少毒性至关重要.
结论:
- 质子疗法为成年扩散性结质瘤提供了传统放射治疗的可行替代方案,提供了类似的生存率.
- 这种模式可以提高治疗耐受性,对神经认知功能保存有潜在的好处.
- 局限性包括追溯数据的占主导地位,强调需要更多的前性研究,标准化患者选择和遵守最新的世卫组织2021年质瘤分类.
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