在克罗恩病患者中,植物性饮食是可行的
Line Birch Arvidsson1, Helle Nygaard Lærke2, Charlotte Lauridsen3
1Department of Gastroenterology, Center for Nutrition and Intestinal Failure, Aalborg University Hospital, Sdr. Skovvej 5, 9000 Aalborg, Denmark; Department of Clinical Sciences, Aalborg University, Denmark.
Clinical nutrition ESPEN
|September 9, 2024
概括
对克罗恩病进行了为期12周的植物性饮食干预,该干预显示了高保留率和改善症状的潜力. 持续的支持对于满足营养需求,特别是蛋白质摄入量至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 临床研究 临床研究
背景情况:
- 克罗恩病的管理往往需要多式模式的方法.
- 植物性饮食显示出作为炎症状况的辅助治疗的前景.
- 需要从干预研究中获得证据来确认克罗恩病的益处.
研究的目的:
- 评估12周植物性饮食干预在克罗恩病患者的可行性.
- 评估植物性饮食对疾病活动和生活质量的影响.
主要方法:
- 一个单臂可行性研究,涉及生物治疗的门诊克罗恩病患者.
- 参与者在12周内接受了指导,以采用基于植物的饮食生活方式.
- 通过招聘,保留和合规来评估可行性;二次结果包括患者报告的结果 (PROM).
主要成果:
- 成功招聘和高保留率 (87.6%) 与15个完成.
- 观察到改善疾病活动得分 (HBI,IBDQ) 的积极趋势,尽管在统计学上不显著.
- 副作用包括蛋白质摄入量降低和肌肉质量减少,突出显示需要营养支持.
结论:
- 植物性饮食干预对于克罗恩病患者来说是可行的,如果有足够的支持.
- 持续的饮食支持对于应对诸如蛋白质需求和抗炎饮食成分等挑战至关重要.
- 需要进一步的研究来优化克罗恩病的植物性饮食干预措施.
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