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Updated: Jun 13, 2025

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设计,合成和评估用于抗SARS-CoV-2活动的新型氧香丁衍生物

Jie Lu1, Yan Cheng2, Yumin Zhang3

  • 1School of Pharmacy, Henan University, Kaifeng 475004, PR China; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.

Bioorganic & medicinal chemistry letters
|September 9, 2024
PubMed
概括

研究人员开发了新型氧甘衍生物来对抗SARS-CoV-2. 几种化合物显示出显著的抗病毒活性,衍生物4a和4d在临床前研究中显示出强大的疗效和改善的药物动力学概况.

关键词:
这是一种Bisbenzylisoquinoline类类化合物.氧康提因衍生品 氧康提因衍生品这就是SARS-CoV-2病毒.

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