预先存在的肝硬化对型肝损伤患者的负面影响:来自创伤质量改善计划数据库的多面性方法
Ting-An Hsu1, Shih-Ching Kang1, Yu-San Tee1
1Department of Trauma and Emergency Surgery, Linkou Chang Gung Memorial Hospital, Chang Gung University, 5, Fu-Hsing Street, Kwei Shan Township, Taoyuan, Taiwan.
概括
预先存在的肝硬化明显恶化了不经手术治疗的突发性肝损伤患者的结果. 经过过导管动脉栓塞 (TAE) 的肝硬化患者的死亡风险更高.
科学领域:
- 创伤外科 手术 创伤外科
- 肝病学 肝病学是一种肝病学.
- 关键护理医学 关键护理医学
背景情况:
- 的肝脏创伤是一种常见的伤害.
- 对于先前存在的肝硬化患者的结局尚未明确.
研究的目的:
- 评估先前存在的肝硬化对非手术治疗的不切割性肝损伤结果的影响.
- 评估通过导管动脉栓塞 (TAE) 在肝硬化患者中的作用.
主要方法:
- 对创伤质量改善计划 (TQIP) 数据库 (2016-2019) 的回顾性分析.
- 患有肝硬化和没有肝硬化的患者的倾向性得分匹配.
- 多变量逻辑回归来确定TAE的影响.
主要成果:
- 肝硬化患者 (1.2%) 的出血,并发症 (AKI,败血症) 和较差的结果 (死亡率,LOS,ICU LOS,呼吸机日) 的比率较高.
- 过导管动脉栓塞 (TAE) 与肝硬化患者的死亡率增加有关 (OR:4.093),但与非肝硬化患者的死亡率增加无关.
结论:
- 预先存在的肝硬化是突发性肝损伤结果的显著负面预测因素.
- 经受TAE治疗以缓解血液静止的肝硬化患者的死亡风险要高得多.
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