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在 laparoscopic 肠切除后,Wuda 颗粒对胃肠功能恢复的有效性:一项随机双盲受控试验

Hai-Ping Zeng¹, Li-Xing Cao², De-Chang Diao³

¹Department of Surgery, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510120, China.

Chinese journal of integrative medicine

|September 9, 2024

概括

伍达颗粒 (WDG) 在腹腔镜肠切除手术后显著加快胃肠功能恢复. 这种传统中医药在手术后增强恢复 (ERAS) 协议中增强康复,显示了患者的改善结果.

科学领域:

胃肠病学和外科康复
药理学和中国传统医学

背景情况:

手术后增强恢复 (ERAS) 协议旨在优化术后护理.
拉帕洛比肠切除可以导致胃肠功能恢复延迟.
确定辅助疗法以加快恢复对于ERAS协议至关重要.

研究的目的:

评估Wuda Granule (WDG) 在 laparoscopic肠切除后改善胃肠功能方面的疗效和安全性.
在ERAS框架内评估WDG作为辅助疗法.
确定WDG对关键康复指标和患者症状的影响.

主要方法:

一个随机,双盲,安慰剂对照试验,涉及108名接受腹腔镜肠切除的患者.
患者从术后1-3天开始每天两次接受WDG或安慰剂,同时接受标准ERAS护理.
主要结局是首次排便的时间;次要结局包括流的时间,食耐受性和症状得分.

主要成果:

107名患者完成了这项研究.
与安慰剂相比,WDG组的第一次排便和浮时间显著缩短 (P=0.012和P=0.040,分别).
在WDG组中观察到改善了胃肠道症状,没有严重的不良事件.

结论:

伍达颗粒 (WDG) 是ERAS协议的潜在有效和安全补充,用于增强腹腔镜肠切除后胃肠功能恢复.
对于男性患者,60岁以下的患者,以及手术时间较短或没有先前腹部手术史的患者,WDG可能会带来特别的好处.
进一步的研究可以探索WDG的机制和手术恢复中的更广泛应用.

关键词:

中国医学中医药是什么?乌达粒子是乌达粒子的一种.加强手术后的康复,改善手术后的恢复.胃肠道功能胃肠道功能腹腔镜肠道切除术腹腔镜肠道切除在手术后出现的阴.随机双盲对照试验是随机的双盲对照试验.

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