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Updated: Jun 13, 2025

TGF-β-mediated Endothelial to Mesenchymal Transition EndMT and the Functional Assessment of EndMT Effectors using CRISPR/Cas9 Gene Editing
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TGF-β-mediated Endothelial to Mesenchymal Transition EndMT and the Functional Assessment of EndMT Effectors using CRISPR/Cas9 Gene Editing

Published on: February 26, 2021

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NORE1A的损失促进了MASLD/MASH的发展.

Howard Donninger1, Katherine Hobbing2, Gavin E Arteel3

  • 1Department of Medicine, University of Louisville, Louisville, KY, USA.

Transgenic research
|September 9, 2024
PubMed
概括

损失NORE1A,一个瘤抑制剂,通过上调SREBP1.1,促进脂肪肝疾病 (MASLD/MASH). NORE1A 缺乏可能会导致人类 MASLD,而 NORE1A 淘汰小鼠提供了一个新的疾病模型.

关键词:
马什 (MASH) 是一个非常重要的产品.马斯尔德 马斯尔德是什么意思在NORE1A中,NORE1A是NORE1A.在RASSF5的基础上.

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