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在单个人类介质干细胞中,线粒体DNA的变异负载

Daniel Hipps1,2, Angela Pyle3, Anna L R Porter3

  • 1The Newcastle Upon Tyne Hospitals NHS Foundation, Newcastle upon Tyne, UK. daniel.hipps@nhs.net.

Scientific reports
|September 9, 2024
PubMed
概括

衰老会在干细胞中积累线粒体DNA (mtDNA) 变异,导致与年龄相关的疾病. 这项研究在人类介质干细胞 (MSC) 中发现了致病性mtDNA变异,这表明在骨质疏松症中发挥了作用.

关键词:
骨疾病是一种骨疾病.介质细胞干细胞 介质细胞干细胞骨质疏松症是一种骨质疏松症.身体 mtDNA 的变异.

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