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Updated: Jun 13, 2025

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需要RBM25来通过ACLYRNA拼接依赖的代谢重新连接来抑制炎症

Yunkai Zhang1,2,3, Ying Gao4, Yujia Wang5

  • 1Naval Medical Center, Naval Medical University, Shanghai, 200433, China.

Cellular & molecular immunology
|September 9, 2024
PubMed
概括

功能障碍的RNA拼接,特别是减少的RNA结合基因蛋白25 (RBM25),通过改变ATP酸酶 (Acly) 拼接和巨细胞代谢来驱动类风湿性关节炎 (RA) 炎症. 针对这个RBM25-Acly轴可以治疗自身免疫性关节炎.

关键词:
简单地说,这是一个很好的选择.基斯乙化 基斯乙化炎症 炎症是一种炎症.代谢重编程是一种代谢重编程.这是RBM2525的标志.分离因子 分离因子.

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