在未经治疗的中国患者中,左心室的结构和功能与的饮食摄入量和脏处理有关
Yi-Bang Cheng1, Chak-Ming Chan1, Ting-Yan Xu1
1Department of Cardiovascular Medicine, Centre for Epidemiological Studies and Clinical Trials, Shanghai Key Laboratory of Hypertension, The Shanghai Institute of Hypertension, National Research Centre for Translational Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
概括
饮食中的摄入量和脏的处理影响左心室结构,特别是在具有特定处理特征的个体中. 血压也在左心室质量指数中起作用.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 高血压研究 高血压研究
背景情况:
- 考虑到血压 (BP),饮食中的,脏的处理以及左心室 (LV) 的结构和功能之间的关系尚未完全理解.
- 左心室缩 (LVH) 是心血管事件的重要危险因素.
- 尿液中的分泌和管状处理是平衡和血压的关键决定因素.
研究的目的:
- 调查饮食中的摄入量和脏中的处理与左心室结构和功能之间的关联.
- 探索与左心室参数相关的分泌,处理和血压之间的相互作用.
主要方法:
- 招募952名未经治疗的患者进行门诊血压监测.
- 心声造影以评估左心室的结构和功能.
- 计算的分数分泌 (FELi) 和的分数远端再吸收率 (FDRNa) 作为近端和远端管状处理的标记.
主要成果:
- 在尿路分泌和FELi之间发现了关于左心室后壁厚度 (LVPW),质量 (LVM) 和质量指数 (LVMI) 的显著相互作用.
- 尿路分泌与LVPW,LVM和LVMI仅在FELi的最低三位数中显著相关.
- 在相互调整的分析中,LVMI与FELi,FDRNa和24小时缩BP有显著的关联. 类似于24小时BP的脏处理指数与LVMI有关.
结论:
- 饮食中的摄入量和处理相互作用,影响左心室结构.
- 脏处理指数与左心室质量指数独立相关,类似于24小时血压.
- 这些发现强调了平衡,功能和心脏重塑之间的复杂相互作用.
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