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Updated: Jun 13, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
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脊髓中代谢物和GBM之间的因果关系:一个双样本的门德尔随机化分析分析

Haijun Bao1,2, Yiyang Chen1, Zijun Meng1

  • 1Department of Forensic Medicine, First College for Clinical Medicine, Xuzhou Medical University, 84 West Huaihai Rd, Xuzhou, Jiangsu, 221000, China.

BMC cancer
|September 9, 2024
PubMed
概括

这项研究使用了门德尔的随机化来识别脑脊液 (CSF) 代谢物因果关系与多种质母细胞瘤 (GBM). 几种代谢物与增加或减少GBM风险有关,为疾病机制提供了洞察力.

关键词:
大脑脊髓液中的脑脊液.在GBMGBMGBMGBMGBM门德尔的随机化代谢产物的代谢物

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相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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