在越南COVID-19爆发期间的同时感染和二次感染
Hong Tham Pham1,2, Thi Ha Truong2, Kim-Huong Truong-Nguyen2
1Faculty of Pharmacy, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam.
患有COVID-19并发感染或二次感染 (CoI/ScI) 的患者面临着明显更高的死亡风险. 这凸显了在住院患者中更好地管理这些感染的必要性.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 同感染/二次感染 (CoI/ScI) 死亡风险在非危急的COVID-19中报告不足.
- 这导致医学文献中的管理不足和出版偏见.
- 研究了住院COVID-19患者的COI/ScI和死亡率之间的关联.
研究的目的:
- 确定共感染/二次感染 (CoI/ScI) 与所有原因死亡率之间的关联.
- 根据病原体类型 (细菌,真菌) 和多药耐药性 (MDR) 来分析死亡风险.
主要方法:
- 越南1466名住院COVID-19患者的回顾性队列研究.
- 将患者分类为非CoI/ScI和CoI/ScI组 (细菌,真菌,MDR).
- 使用了时间依赖性分析,Poisson回归和Cox比例危险回归.
主要成果:
- 总体而言,CoI/ScI组的死亡率为26.4%,而非CoI/ScI组的死亡率为22.1%.
- CoI/ScI与3.27倍的死亡风险增加有关 (调整后HR为3.27).
- 带有$\ge$1 MDR病原体的细菌CoI/ScI和CoI/ScI显示出更高的死亡风险 (HR分别为3.79和3.89).
结论:
- 在COVID-19患者中,无论耐药性状况如何,CoI/ScI显著增加了全因死亡风险.
- 需要进一步的研究来确认真菌和混合真菌-细菌COI/ScI的死亡风险.
更多相关视频
12:21A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
Published on: September 28, 2022
08:41Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
相关概念视频
Viral Recombination
Pneumonia III: Complications and Assessment
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Pneumonia II: Pathophysiology
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
