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在中国接受血液透析的患者中,高胆固醇血量负担和治疗模式:前性多中心队列研究 (PRECEDE-K) 的最终分析
Haijiao Jin1, Renhua Lu1, Lihong Zhang2
1Department of Nephrology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Renal failure
|September 10, 2024
概括
超血症 (HK) 在中国血液透析 (HD) 患者中很常见,超过75%的人经历了复发. 结合剂的使用非常低,突出显示了末期脏疾病 (ESRD) 的HK管理中的差距.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内部医学 内部医学
- 心脏病学 心脏病学
背景情况:
- 末期病 (ESRD) 接受血液透析 (HD) 的患者面临高血症 (HK) 的显著风险,这种疾病与心律失常和突然死亡有关.
- 有限的数据存在于HK的流行和管理在中国的HD人口中,需要进一步调查这一关键的健康问题.
研究的目的:
- 评估治疗方式,复发率和高卡血病 (HK) 的总体患病率,在中国接受血液透析的末期脏病 (ESRD) 患者中.
- 为了确定这个患者队伍当前的HK管理策略中的差距.
主要方法:
- 一项前性队列研究涉及600名患有ESRD或HD的成年患者,该研究于2021年5月至2022年7月在中国的15个中心进行.
- 数据收集的重点是6个月内HK的发病率和复发,以及对包括结合剂在内的处方治疗方法的分析.
主要成果:
- 观察到HK的高患病率,75.5%的患者在6个月内至少经历过一次发作,受影响者中复发率为78.6%.
- 尽管复发率很高,但结合剂的利用率显著低,只有5.3%的HK患者接受了这些治疗.
- 使用的特定结合剂包括聚二硫酸盐 (1.5%),聚二硫酸盐 (2.9%) 和环酸盐 (1.3%).
结论:
- 高血症 (HK) 对血液透析 (HD) 患者来说是一个慢性挑战,强调需要持续有效的管理策略.
- 在这群中国人群中,结合剂的处方率很低,这表明对改善治疗干预措施来管理HK的重大未满足需求和潜力.
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