细菌角膜炎和水凝隐形眼镜使用者的严重疾病的危险因素:一个多中心病例对照研究和病例分析
Loretta B Szczotka-Flynn1, Sangeetha Raghupathy, Soham Shah
1Case Western Reserve University (CWRU) (L.B.S.-F., S.R., S.K.I.), Department of Ophthalmology & Visual Sciences and University Hospitals of Cleveland Eye Institute, Cleveland, OH; Department of Ophthalmology (K.S.), Indiana University, Cleveland, OH; CWRU School of Medicine (S.S.), Cleveland, OH; CWRU Department of Population and Quantitative Health Sciences (L.B.S.-F., S.K.I.), Cleveland, OH; and Department of Public Health Sciences (F.B.), University of Miami, Cleveland, OH.
Eye & contact lens
|September 10, 2024
概括
没有特定的隐形眼镜 (CL) 因素会增加细菌角膜炎的风险. 然而,目前的吸烟者和可重复使用的CL佩戴者面临严重的疾病风险,而每日一次性CL提供保护.
科学领域:
- 眼科医生 眼科 眼科
- 微生物学 微生物学
背景情况:
- 细菌性角膜炎是一种严重的隐形眼镜 (CL) 相关并发症.
- 识别风险因素对于预防和管理至关重要.
研究的目的:
- 评估与CL相关的细菌角膜炎的风险因素.
- 用单个病例分析来确定与严重疾病相关的CL因素.
主要方法:
- 一项病例控制研究招募了153例细菌角膜炎病例和158名高风险的CL佩戴者.
- 调查问卷收集了有关人口统计,CL类型,磨损和处理的数据.
- 后勤回归分析了CL变量与角膜炎严重程度之间的关联.
主要成果:
- 病例年龄较大,更有可能是男性,而且吸烟者比对照者更频繁.
- 在CL物质/类型和角质炎发生之间没有发现显著的关联.
- 目前的吸烟者和可重复使用镜片的佩戴者有严重疾病的风险增加.
结论:
- 没有特定的CL因子与细菌性角质炎的发生有关.
- 每天一次性使用的CL显示出对严重疾病的保护作用.
- 吸烟和佩戴可重复使用的透镜是严重的CL相关细菌性角膜炎的危险因素.
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