患有肥胖症的跨性别成年人心血管事件的患病率:基于人口的分析分析
Adhvithi Pingili1, Roopeessh Vempati2, Madhusha Vemula3
1Department of Internal Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Obesity pillars
|September 10, 2024
概括
肥胖显著增加了跨性别成年人的心血管风险,包括主要的不良心血管和脑血管事件 (MACCE) 和心脏骤停. 这凸显了针对这一群体进行有针对性的干预和进一步研究的必要性.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 肥胖对心血管 (CV) 事件的影响在 cisgender 群体中得到了充分证实.
- 有限的研究存在于CV事件风险与肥胖相关的跨性别个人.
研究的目的:
- 为了确定跨性别成年人中肥胖的患病率.
- 调查跨性别个体中肥胖和CV事件之间的关联.
主要方法:
- 使用2020年美国全国住院患者样本进行的回顾性队列研究.
- 识别跨性别患者,并将其分为肥胖和非肥胖队列.
- 对住院死亡率,心肌梗塞,中风,心脏骤停,肺栓塞和MACCE进行多变量回归分析.
主要成果:
- 在19,345名跨性别者入院中,有15.3%的人患有肥胖症.
- 肥胖队列显示高血压,糖尿病和高脂血症的比率更高.
- 肥胖的变性患者的MACCE (OR 2.1) 和心脏骤停 (OR 3.92) 的几率显著增加.
结论:
- 肥胖与变性人群中MACCE和心脏骤停的几率更高有关.
- 相关的心血管风险因素,如高血压和糖尿病,可能会导致这些结果.
- 需要进一步的研究来阐明肥胖对跨性别人口CV结果的全部影响.
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