鱼类和贝类过敏:在英国和美国的呈现和管理差异-对945名患者的分析
Alla Nakonechna1,2,3, Ard van Bergen4, Ariharan Anantharachagan5
1University of Liverpool, Liverpool, United Kingdom.
The journal of allergy and clinical immunology. Global
|September 10, 2024
概括
海鲜过敏 (SA) 管理在美国和英国的过敏症诊断和上腺素自注射器使用中显示出显著的差距. 需要标准化的诊断协议,以更好地照顾这种常见的食物过敏患者.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 临床医学 临床医学
- 公共卫生 公共卫生
背景情况:
- 海鲜过敏 (SA),包括贝类和鱼类,是过敏反应的主要原因.
- 关于海鲜过敏的临床管理,国际数据有限.
- 喘影响着大量患者群体,需要标准化的护理协议.
研究的目的:
- 描述一大群患有鱼类和贝类过敏的患者.
- 为了确定美国和英国之间SA临床管理的差异.
- 促进未来对海鲜过敏的护理标准化.
主要方法:
- 一项回顾性,观察性,非干预性研究,涉及2015年至2019年945名患者.
- 从美国和英国的7家医院收集的数据.
- 奇平方测试用于比较不同国家的患者病史和症状.
主要成果:
- 在SA患者中,过敏反应的低诊断与两个国家内不充分使用上腺素自注射器有关.
- 喘和过敏性鼻炎在美国患者中更为普遍;湿疹在英国患者中更为常见.
- 与美国患者相比,英国患者报告呼吸道,胃肠道和神经系统症状的比率更高.
结论:
- 在国际多中心队列中,有机会改善海鲜过敏管理.
- 医生对过敏反应的鉴定,诊断口服食物挑战和上腺素治疗需要在美国和英国进行改进.
- 建议过敏学家和实习生制定统一的,标准化的SA诊断协议.
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